2025
Structural mechanisms for cold-adapted activity of phosphoenolpyruvate carboxykinase
*McLeod, M. J., Yazdani, S., Barwell, S. A. E., Holyoak, T.
Protein Science 34 (11), 1-14
JA Indergaard, K Mahmood, L Gabriel, G Zhong, A Lastovka, MJ McLeod, RE Thorne.
IUCrJ 12 (3), 1-12
A structural perspective on the temperature dependent activity of enzymes
*MJ McLeod, SAE Barwell, T Holyoak, RE Thorne
Structure 33 (1), 1-11
2024
Ice formation and its elimination in cryopreservation of oocytes
AW Abdelhady, DW Mittan-Moreau, PL Crane, MJ McLeod, SH Cheong, RE Thorne.
Scientific Reports 14 (1), 18809
2023
The H163A mutation unravels an oxidized conformation of the SARS-CoV-2 main protease
N Tran, S Dasari, SAE Barwell, MJ McLeod, S Kalyaanamoorthy, T Holyoak, A Ganesan.
Nature Communications 14 (1), 5625
MJ McLeod, T Holyoak
Proteins: Structure, Function, and Bioinformatics 91 (9), 1261-1275
Identifying structural and dynamic changes during the Biliverdin Reductase B catalytic cycle
E Lee, MJ McLeod, JS Redzic, B Marcolin, RE Thorne, P Agarwal, EZ Eisenmesser
Frontiers in Molecular Biosciences 10, 1244587
MJ McLeod, N Tran, GD McCluskey, TD Gillis, SL Bearne, T Holyoak
Protein Science 32 (6), e4648
2021
Enzymes| Phosphoenolpyruvate Carboxykinases
MJ McLeod, T Holyoak
Elsevier
JA Clinger, DW Moreau, MJ McLeod, T Holyoak, RE Thorne
IUCrJ 8 (5), 784-792
Media Press Release: https://news.cornell.edu/stories/2021/09/freeze-researchers-develop-new-protein-crystallography-tool
2019
MJ Mcleod, AP Krismanich, A Assoud, GI Dmitrienko, T Holyoak
Biochemistry 58 (37), 3918-3926
2017
DS Cui, A Broom, MJ Mcleod, EM Meiering, T Holyoak
Biochemistry 56 (15), 2106-2115
2016
TA Johnson, MJ Mcleod, T Holyoak
Biochemistry 55 (3), 575-587
2015
MD Balan, MJ Mcleod, WR Lotosky, M Ghaly, T Holyoak
Biochemistry 54 (38), 5878-5887
*Corresponding Author